Transcranial direct current stimulation for improving idiopathic Parkinson’s syndrome.

Idiopathic Parkinson’s disease (IPD) is a neurodegenerative disorder. The severity of disability usually increases with disease duration and affects patients’ impairment, disability and health-related quality of life. A possible adjunct to improve outcomes in patients with IPD might be transcranial direct current stimulation (tDCS) to modulate cortical excitability and hence improving outcomes in people with IPD.¬†Two authors independently extracted data and assessed trial quality. We included six trials with 137 participants. There was no effect of tDCS compared to sham tDCS in our primary outcome measure, impairment, as measured by the proportional change of the Unified Parkinson’s Disease Rating Scale (UPDRS) (mean difference (MD) -7.10 %, 95% confidence interval (CI) -19.18 to 4.97; P = 0.25). There was evidence of an effect on UPDRS part III motor subsection score at the end of the intervention period (MD -14.43%, 95% CI -24.68 to -4.18; P = 0.006). There was no evidence of an effect regarding the reduction in off time and on time with dyskinesia (MD 0.10 hours, 95% CI -0.14 to 0.34; P = 0.41; and MD 0.00 hours, 95% CI -0.12 to 0.12; P = 1, respectively). There was no evidence of an effect for gait speed, health related quality of life and safety/acceptability, measured by dropouts and adverse events (including death).

There is insufficient evidence to determine the effects of tDCS in reducing off time and on time with dyskinesia and for improving health-related quality of life, disability and impairment in patients with IPD.

neurological rehabilitation for physiotherapy and physical therapy

Introduction to Neurology

Treating those with neurological impairments can seem complex and overwhelming at times. Get to grips with the basics and build strong foundations with the online introduction to neurology course.

Speak your mind

Your email will not be published.