The objective of this study was to examine the effects of an active neurodynamic mobilization program on pain, neurodynamics, perceived health state, and fatigue in patients with fibromyalgia syndrome (FMS). 48 patients were included in this RCT and they were randomly allocated to an active neurodynamic mobilisation program or a control group, interventions were performed twice a week. Pain was assessed with the Brief Pain Inventory and Pain Catastrophizing Scale; neurodynamics were evaluated using neurodynamic tests for upper and lower limbs. The functional state was evaluated with the Health Assessment Questionnaire Disability Index, and perceived fatigue was evaluated with the Fatigue Severity Scale. Significant (P<.05) between-groups differences were found in the values of pain, upper and lower limb neurodynamics, functional state, and fatigue. Also, significant pre- to postintervention within-group differences were found in the intervention group, whereas no significant changes were found in the control group.
A neurodynamic mobilization program is effective in improving pain, neurodynamics, functional status, and fatigue in patients with FMS.