Functional Reach, Depression Scores & Number of Meds are Associated with Falls in People with Stroke.

Falls are a common adverse event among people with stroke. Previous studies investigating risk of falls after stroke have relied primarily on retrospective fall history ranging from 6-12 months recall, with inconsistent findings. The aim of this study was to identify factors and balance assessment tools that are associated with number of falls in individuals with chronic stroke.

Study participants completed baseline testing and were prospectively asked about falls. A multivariate negative binomial regression was used to identify baseline predictive factors predicting falls: age, endurance (6 minute walk test), number of medications, motor control (Fugl-Meyer lower extremity score), depression (Patient Health Questionnaire-9), physical activity (number of steps per week), and cognition (Mini Mental Status Exam score). A second negative binomial regression analysis was used to identify baseline balance assessment scores predicting falls: gait velocity (comfortable10 Meter Walk), Berg Balance Scale (BBS), Timed Up and Go (TUG), and Functional Reach Test (FRT). Receiver operating characteristic (ROC) and the area under the curve (AUC) were utilized to determine the cutoff scores for significant predictors of recurrent falls.

Baseline measures that significantly predicted number of falls included increased number of medications, higher depression scores and decreased FRT. Cutoff scores for number of medications were 8.5 with AUC of 0.68. Depression scores differentiated recurrent fallers at a threshold of 2.5 scores with AUC of 0.62. FRT differentiated recurrent fallers at a threshold of 18.150 cm with an AUC of 0.66.

Number of medications, depression scores and decreased FRT distance at baseline were associated with increased number of falls. Increased medications might indicate multiple comorbidities or polypharmacy effect, increased depression scores may indicate psychological status, and decreased functional reach distance could indicate dynamic balance impairments.

Pharmacology and Physiotherapy

This online course will review the effects, side effects, potential drug interactions and how these will influence ideal physical therapy management with a specific focus on antidepressants and exercise.

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