A Literature Review of Pediatric Spinal Manipulation and Chiropractic Manipulative Therapy

The reason for this study was to perform a literature search to identify relevant studies on pediatric spinal manipulation and chiropractic manipulative therapy and to evaluate if safety terminology was consistent with the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). Of the 9 relevant articles identified in this study, 3 reported methodology for classifying safety incidents, and all 9 used safety terminology (adverse effects or adverse events). Although, use of terminology was inconsistent.

Most of the articles identified in this literature review did not use terminology consistent with the standards established by the ICH when reporting on safety incidents following pediatric spinal manipulation or chiropractic manipulative therapy. Additional efforts should be taken to include consistent terminology for studies of spinal manipulation and chiropractic manipulative therapy for children.