Mechanisms of Neuromuscular Dysfunction in Critical Illness

Kahn J., Harrison T.B., Rich M.M.

The development of neuromuscular dysfunction during critical illness is increasingly recognized as a cause of failure to wean from mechanical ventilation and is associated with significant morbidity and mortality. This article describes the clinical spectrum of acquired neuromuscular weakness in patients with critical illness. It also provides an approach to diagnosis and discusses the pathogenesis of this entity.

Critical Care Clinics 2008; 24: 165 – 177

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