Gerard J. Hutten, Leo A. van Eykern, Philipp Latzin, Manuela Kyburz, Wim M. van Aalderen, Urs Frey.
|This study investigates the hypothesis that infants dynamically regulate their tidal flow and end-expiratory volume level by studying the interaction between muscle activity, flow and lung volume in spontaneously sleeping neonates.|
|They measured the relative impact of intercostal and diaphragmatic EMG activity in direct comparison to the resulting tidal flow and FRC on 20 healthy babies.|
Results showed that lung mechanical function is dynamically regulated and adapts on a breath to breath basis.
Pediatr Pulmonol., published on-line 30/07/2008