Association between obesity and depressive disorder in adolescents at high risk for depression

The authors aimed to examine the relationship between Body Mass Index (BMI) and depressive disorder in adolescents at high risk for depression. The authors did a prospective longitudinal 3-wave study of offspring of parents with recurrent depression. Replication in population-based cohort study.

Three hundred and thirty-seven families where offspring were aged 9-17 years at baseline and 10-19 years at the final data point. Replication sample of adolescents from population-based cohort study aged 11-13 years at first assessment and 14-17 years at follow-up. Measurements was done using high risk sample used BMI, skin-fold thickness, Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV)-defined major depressive disorder and depression symptoms using the Child and Adolescent Psychiatric Assessment (CAPA). Replication sample used BMI, DSM-IV depressive disorder and depression symptoms using the Development and Well-Being Assessment (DAWBA).

The authors concluded that BMI does not significantly predict the development of depression in the offspring of parents with recurrent depression.

Pharmacology and Physiotherapy

This online course will review the effects, side effects, potential drug interactions and how these will influence ideal physical therapy management with a specific focus on antidepressants and exercise.