Acute Opioid Administration Improves Work-Related Exercise Performance in Patients With Chronic Back Pain

Douglas P. Gross, Yagesh Bhambhani, Mark J. Haykowsky, Saifudin Rashiq

This study axamines the impact of acute opioid administration on work-related exercise performance in patients with chronic back pain. Subjects performed a continuous lifting and lowering test to voluntary fatigue at a load equivalent to 33% of their predetermined maximal lifting load twice: Once after receiving a single intravenous dose of 1 ?g/kg fentanyl (a narcotic analgesic) and once after saline placebo.

This article presents the results of a clinical trial showing that acute opioid administration improves work-related exercise performance in individuals with chronic back pain. Longer trials of the effectiveness of opioid analgesia as an adjunct to functional restoration programs are recommended.

The Journal of Pain, 2008, 9(9), 856-862

Link to Abstract

Neck Pain

Out of all 291 conditions studied in the Global Burden of Disease 2010 Study, neck pain ranked 4th highest in terms of disability and 21st in terms of overall burden.

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