Improvements in Symptoms and Quality of Life following Exercise Training in Older Adults with Moderate/Severe Persistent Asthma.

The objective of this study was to investigate whether exercise training improves functional exercise capacity and QOL in middle-aged and older adults with fixed airway obstruction asthma (FAOA). Methods: 35 subjects aged 67.8 +/- 10.6 years, with FEV(1) 59 +/- 16% of predicted, were randomised to a 6-week ‘intervention’ period of supervised exercise training (n = 20) or usual care (n = 15). This period was preceded by a 3-week run-in period during which asthma control was assessed weekly. Functional exercise capacity (6-min walk distance, 6MWD) and QOL (Asthma QOL Questionnaire, AQLQ) were measured before, immediately following and 3 months after the intervention period. 34 subjects completed the intervention period. Relative to the control group, the exercise group had greater improvements immediately following and 3 months after the intervention in the AQLQ symptom domain and AQLQ activity limitation domain. 6MWD increased in the exercise group immediately following training and remained elevated at the 3-month follow-up. The magnitude of change in 6MWD between groups was not significant, despite no change in the control group.

Supervised exercise training improves symptoms and QOL in adults with FAOA.

Turner S, Eastwood P, Cook A, Jenkins S. Improvements in Symptoms and Quality of Life following Exercise Training in Older Adults with Moderate/Severe Persistent Asthma. Respiration. 2010 May 22;

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