A randomized controlled trial to compare two botulinum toxin injection techniques on the functional improvement of the leg of children with cerebral palsy.

The objective of this study was to compare the efficacy of botulinum toxin type A injection guided by different localizing techniques, electrical stimulation and palpation, to treat spasticity of the ankle plantar flexors.  Sixty-five children with spastic hemiplegic or diplegic cerebral palsy underwent botulinum toxin injection guided by electrical stimulation or palpation, and two weeks of physiotherapy.  Three groups improved significantly. The mean improvements between baseline and the end of follow-up were respectively 20, 16.2 and 11.9 degrees for passive ROM, -1.9, -1.4 and -0.7 for modified Ashworth Scale scores, -5.8, -4.2 and -2.3 for Composite Spasticity Scale scores, 18.6, 11.3 and 6.9 for Gross Motor Function Measure scores, and 0.2, 0.1 and 0.1 m/s for walking velocity in the botulinum toxin group guided by electrical stimulation injection plus physiotherapy, the botulinum toxin group guided by palpation injection plus physiotherapy, and the physiotherapy only group. The botulinum toxin injection guided by electrical stimulation group showed greater improvement in passive ROM, modified Ashworth Scale scores, Composite Spasticity Scale scores, and Gross Motor Function Measure scores than the other two groups after treatment for three months.

Botulinum toxin injection guided by electrical stimulation plus physiotherapy is likely to be best in improving spasticity and functional performance in children with cerebral palsy.

Kaishou Xu, Tiebin Yan, Jianning Mai. A randomized controlled trial to compare two botulinum toxin injection techniques on the functional improvement of the leg of children with cerebral palsy. Clin Rehabil. 2009 Sep;23(9):800-11.

neurological rehabilitation for physiotherapy and physical therapy

Introduction to Neurology

Treating those with neurological impairments can seem complex and overwhelming at times. Get to grips with the basics and build strong foundations with the online introduction to neurology course.

Speak your mind

Your email will not be published.