Short- and long-term effects of endurance training in patients with mitochondrial myopathy.

It is unknown whether prolonged training is a safe treatment to alleviate exercise intolerance in patients with mitochondrial DNA (mtDNA) mutations. The effect of 3 and 12 months training and 3-12 months deconditioning was studied in four patients carrying different mtDNA mutations.  Three-month moderate-intensity training increased oxidative capacity by 23%, which was sustained after 6-12 [...]

Advantages of group treatment and structured exercise in promoting short-term weight loss and cardiovascular risk reduction in adults with central obesity.

Previous data suggest that group obesity treatment results in greater weight loss than individual treatment. Whether exercise with calorie restriction results in significantly greater weight loss as compared with calorie restriction alone remains unclear. We evaluated the impact of self-selected group intervention, with and without exercise, on body mass index (BMI) and cardiovascular risk factors. [...]

Exercise training-induced changes in heart rate recovery in obese men with metabolic syndrome

Heart rate recovery (HRR) as a function of vagal reactivation, which is an independent risk predictor for cardiovascular disease and mortality, is strongly associated with metabolic syndrome. Middle-aged obese men classified on the basis of Adult Treatment Panel III criteria were investigated in this study. Postexercise HRR and the HRR decay constant following a symptom-limited [...]

Pre-diabetes ‘timebomb’ warning

An estimated seven million people in the UK have early warning signs of diabetes, a charity has warned.  People with pre-diabetes have higher than normal blood sugar levels and a 12 times increased risk of developing full-blown type 2 diabetes.  Diabetes UK called pre-diabetes, which can cause long-term damage but is reversible with exercise, weight [...]

Gait Variability Detects Women in Early Postmenopause With Low Bone Mineral Density.

This study was an observational cohort design with participants assigned to groups on the basis of BMD status. Fifty-four women, 31 with low BMD and 23 with normal BMD, participated. Physical performance was measured by assessment of dynamic balance (timed backward tandem walk test), strength (handheld dynamometry of isometric quadriceps muscle force production), and free [...]

School-based exercise program improves fitness, body composition and cardiovascular risk profile in overweight/obese children.

This study determined the effect of a school-based exercise training (ET) without dietary intervention, on body composition, fitness and cardiovascular risk in overweight/obese children. Subjects were 51 overweight/obese 6.5- to 12.5-year-old children, of whom 48 completed the program. Participants were enrolled in a 15-week aerobic training (three 60-minute sessions/week). Working heart rate was between 120-185 [...]

Effects of exercise training intensity on nocturnal growth hormone secretion in obese adults with the metabolic syndrome.

Irving BA, Weltman JY, Patrie JT, Davis CK, Brock DW, Swift D, Barrett EJ, Gaesser GA, Weltman A The objective of this study was to examine the effects of 16 wk endurance training on spontaneous 12-h overnight GH secretion in adults with the metabolic syndrome. 34 adults with the metabolic syndrome were randomized to one [...]

High-Calorie-Expenditure Exercise A New Approach to Cardiac Rehabilitation for Overweight Coronary Patients

Ades PA, Savage PD, Toth MJ, Harvey-Berino J, Schneider DJ, Bunn JY, Audelin MC, Ludlow M.   A randomized controlled clinical trial was designed to evaluate the effect of high-calorie expenditure exercise (3000- to 3500-kcal/wk exercise-related energy expenditure) compared with standard cardiac rehabilitation (CR) exercise (7 to 800 kcal/wk) on weight loss and risk factors [...]

Positive effect of long-term tailored physical activity therapy on diabetes mellitus management in an obese type 2 diabetic patient.

Szabó M, Pelíšková P, Kvapil M, Matouš M The case history of a 44-year-old, severely obese Caucasian man with serious decompensation of diabetes and subsequent withdrawal of high-dose insulin is reported. Insulin was withdrawn after 5 years of continuous therapy and the patient was treated for 6 months with diet, individualized physical therapy and oral [...]