Effects of oxygen on exercise duration in chronic obstructive pulmonary disease patients before and after pulmonary rehabilitation.
Supplemental oxygen therapy has been shown to improve exercise performance in patients with chronic obstructive pulmonary disease (COPD). It is unknown whether the magnitude of this benefit would be affected by participation in a pulmonary rehabilitation program. The objective of this study was to compare the effects of supplemental oxygen on exercise capacity in nonhypoxemic [...]
Six-minute walk distance in patients with severe end-stage COPD: association with survival after inpatient pulmonary rehabilitation.
The purpose of this study was to evaluate the relationship between the 6-minute walk distance (6MWD) and survival in a cohort of patients with severe end-stage chronic obstructive pulmonary disease (COPD) who received inpatient pulmonary rehabilitation (IPR) from 1995 to 2007. We retrospectively analyzed 815 patients with severe end-stage COPD who received IPR. 6MWDs before [...]
Pulmonary rehabilitation is successful for COPD irrespective of MRC dyspnoea grade.
It is not clear whether the benefits of pulmonary rehabilitation (PR) apply equally to patients with Chronic Obstructive Pulmonary Disease (COPD) with different levels of starting disability. We have therefore investigated the effect of pulmonary rehabilitation stratified by the MRC dyspnoea scale in patients with COPD. This is a retrospective, observational study of data collected [...]
A randomised controlled equivalence trial to determine the effectiveness and cost-utility of manual chest physiotherapy techniques in the management of exacerbations of chronic obstructive pulmonary disease (MATREX).
The objective of this study was to estimate the effect, if any, of manual chest physiotherapy (MCP) administered to patients hospitalised with chronic obstructive pulmonary disease (COPD) exacerbation on both disease-specific and generic health-related quality of life. To compare the health service costs for those receiving and not receiving MCP. 526 participants aged 34-91 years [...]
Conical-PEP is safe, reduces lung hyperinflation and contributes to improved exercise endurance in patients with COPD: a randomised cross-over trial.
Question: Does a new positive expiratory pressure device (conical-PEP) decrease lung hyperinflation during exercise in patients with chronic obstructive pulmonary disease compared to normal breathing? Does it increase the duration of exercise? Thirteen patients with moderate to severe chronic obstructive pulmonary disease (mean FEV1 61% predicted) participated. The experimental intervention was conical-PEP breathing with a [...]
Pulmonary rehabilitation for chronic obstructive pulmonary disease: clinical, economic, and budget impact analysis
The objectives of this assessment were to evaluate the effect of PR programs for COPD on clinical and economic outcomes, and to assess their health services impact. The research questions were: ? What is the clinical effectiveness of PR and pharmacotherapy (together) compared with pharmacotherapy alone for adults with COPD? ? What is the effectiveness [...]
Short- and long-term efficacy of a community-based COPD management programme in less advanced COPD: a randomised controlled trial.
The effectiveness of pulmonary rehabilitation in advanced COPD is well established, but few data are available in less advanced disease. In a 2 year randomised controlled trial, 199 patients with an average moderate airflow obstruction but impaired exercise capacity (mean (SD) forced expiratory volume in 1 s (FEV(1)) 60 (16)%, peak work load (Wmax) <70%) [...]
Long-term effects of 1-year maintenance training on physical functioning and health status in patients with COPD: A randomized controlled study.
The purpose of this study was to examine whether maintenance training (MT) for 1 year improved the long-term effects of a 7-week chronic obstructive pulmonary disease (COPD) rehabilitation program. After a 7-week outpatient rehabilitation program, 96 patients with COPD were randomized to either an MT group (n = 55) or a control group (n = [...]
(Cost)-effectiveness of self-treatment of exacerbations on the severity of exacerbations in patients with COPD: the COPE II study.
Chronic obstructive pulmonary disease (COPD) is a chronic disease with a high prevalence and rapidly increasing incidence rates. The effect of self-treatment of COPD exacerbations on the severity of exacerbations during a 1-year period was examined and a cost-effectiveness analysis was performed. Patients were randomly allocated to four 2-hour self-management sessions, with or without training [...]
Efficacy and Costs of Nutritional Rehabilitation in Muscle-Wasted Patients With Chronic Obstructive Pulmonary Disease in a Community-Based Setting: A Prespecified Subgroup Analysis of the INTERCOM Trial
In a 2-year RCT, 199 COPD patientswith moderate airflow obstruction  (FEV1%pred. 60%) and impaired exercise capacity were randomized to the interdisciplinary community-based COPD management program (INTERCOM) or usual care (UC). A prescheduled subgroup analysis was performed on 39 of the 199 patients who were muscle wasted and received UC or nutritional therapy in combination with [...]
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