Sensory Neurons and Fibers from Multiple Spinal Cord Levels Innervate the Rabbit Lumbar Disc.
Zhang, Yejia MD, PhD; Kerns, James M. PhD; Anderson, D Greg MD; Lee, Young Sang MD; Chen, Er-Yun MD; Tannoury, Chadi MD; An, Howard S. MD The objective of this study was to establish the neurotransmission pathway from the lumbar L5/6 intervertebral disc (IVD) to the spinal cord in the rabbit. Fluorogold particles injected into [...]
The Degenerated Lumbar Intervertebral Disc is Innervated Primarily by Peptide-Containing Sensory Nerve Fibers in Humans.
Ozawa, Tomoyuki MD; Ohtori, Seiji MD; Inoue, Gen MD; Aoki, Yasuchika MD; Moriya, Hideshige MD; Takahashi, Kazuhisa MD The purpose of this study was to determine the type of sensory fibers innervating human degenerated lumbar intervertebral discs. A degenerated, painful lumbar intervertebral disc was harvested from each of 8 patients during surgery. Sections were immunostained [...]